U.S. stocks closed remarkably lower on Wednesday, as persistent fears over an imminent recession struck a blow to the already-dampened investor sentiment. 

The Dow plunged 800.49 points, or 3.05 percent to 25,479.42, marking the largest daily decline of the year so far. The S&P 500 decreased 85.72 points, or 2.93 percent, to 2,840.60. The Nasdaq Composite Index fell 242.42 points, or 3.02 percent, to 7,773.94. 

All of the 11 primary S&P 500 sectors traded lower around market closing, with the energy sector down nearly four percent, leading the losers. 

The financial sector was also among the worst performers, pulling back around 3.4 percent. Major bank shares extended losses, including Bank of America, Citigroup and JP Morgan.

Macy's shares plunged by over 13.2 percent after the U.S. department store chain reported second-quarter earnings below market estimates. The retailer also cut back its profit outlook for the full year by 20 cents. 

The bond market flashed worrying signals over a looming recession on Wednesday, as the yield of the U.S. 10-year Treasury note broke below the yield of the two-year bill at some point, marking the first time in 12 years. 

The spread formed a so-called inverted yield curve, which is widely considered as a harbinger of a future economic recession. It is generally accepted that recessions typically arrive within 18 to 24 months following the inverted yield curves. 

Yields of the U.S. long-term and short-term Treasury bills all pulled back on Wednesday. Market jitters drove the 30-year Treasury bill yield to strike an all-time low of a bit over two percent, fueling panic over the health of both the United States and global economies. 

The Cboe Volatility index, widely considered the best fear gauge in the stock market, surged 26.14 percent to 22.1 on Wednesday.