Rebels shot down a Syrian warplane in the opposition stronghold of the northwestern Syrian Idlib province on Wednesday as the government forces closed in on a strategically important town.

The Syrian state news agency SANA said the warplane had been hit by an anti-aircraft missile fired by militants while on a mission “to destroy headquarters of the Nusra Front,” a jihadist group now known as Tahrir al-Sham.

Tahrir al-Sham, the most powerful insurgent group in the area, said its fighters had shot down a Sukhoi 22 jet that had taken off from a Syrian air base in Homs province. It did not say how the jet had been brought down.

SANA said the pilot's fate was unknown. The Syrian Observatory for Human Rights, which reports on the war using a network of sources, said a pilot who ejected from the plane had been captured by insurgents.

The Observatory said heavy machine guns had been used to shoot down the jet.

The jet was downed near Khan Sheikhoun, a rebel-held town now being targeted by the government offensive.

Government forces seized new ground from rebels near Khan Sheikhoun on Wednesday, advancing to within a few kilometers of the town. A rebel commander told Reuters that the town, in opposition hands since 2014, was in “great danger.”

Dozens of people were killed in Khan Sheikhoun in 2017 in a poison gas attack that prompted U.S. President Donald Trump to order a missile strike against the Syrian air base from where the United States said it had been launched.

An investigation conducted by the United Nations and the Organization for the Prohibition of Chemical Weapons said the Syrian government was responsible for releasing sarin on the town on April 4, 2017. Damascus denies using such weapons.

Syrian rebels have shot down government planes on several occasions during the war that spiraled out of the uprising against President Bashar al-Assad in 2011.

The Idlib region is part of the last major stronghold of the opposition to the Syrian government.

The government had struggled to make any gains in the area in an offensive that got underway in late April. It has managed to take several significant positions, including the town of al-Habeet on Saturday. The advance toward Khan Sheikhoun threatens to encircle the last remaining pocket of rebel-held territory in neighboring Hama province, including the towns of Morek, Kafr Zeita and Latamneh.

The humanitarian adviser to the UN Special Envoy for Syria said the new surge in violence in the northwest threatened the lives of millions after more than 500 civilians were killed since late April.

Tahrir al-Sham is the latest incarnation of the group formerly known as the Nusra Front, which was al Qaeda's official wing in the Syrian conflict until they parted ways in 2016.

The group is designated as a terrorist organization by the UN Security Council.