The Trump administration on Thursday ordered the expulsion from the United States of two members of Cuba's delegation to the United Nations and restricted travel of the remaining mission members to Manhattan, drawing strong condemnation from Havana.

The announcement came as the United Nations General Assembly is holding its 74th session in New York. The U.S. State Department accused the two Cuban diplomats of trying to "conduct influence operations" harmful to U.S. national security but did not elaborate on the accusations or release their names.

It was the latest sign of deteriorating U.S. relations with Cuba, focusing especially on Havana's support for Venezuela's President Nicolas Maduro, since U.S. President Donald Trump took office in January 2017.

"The Department of State today notified the Cuban Ministry of Foreign Affairs that the United States requires the imminent departure of two members of Cuba's Permanent Mission to the United Nations for abusing their privileges of residence," State Department spokeswoman Morgan Ortagus said in a statement.

"This is due to their attempts to conduct influence operations against the United States," she said.

Cuban Foreign Minister Bruno Rodriguez rejected the U.S. actions as "unjustified," saying on Twitter: "The imputation that they might have carried out actions incompatible with their diplomatic status is a vulgar slander."

"The expulsion ... has the aim of provoking a diplomatic spiral that would lead to the closure of bilateral embassies, further tightening of the (U.S.) blockade and creation of tensions between both countries," he said.

Ortagus said the movements of other members of the Cuban delegation would "essentially be limited to the island of Manhattan," according to the statement.

"We take any and all attempts against the national security of the United States seriously, and will continue to investigate any additional personnel who may be manipulating their privileges of residence."

Under the 1947 UN "headquarters agreement," the United States is generally required to allow access to the United Nations for foreign diplomats. But Washington says it can deny visas for "security, terrorism, and foreign policy" reasons, though this provision is only invoked on a limited basis.

Over the decades, Washington and Havana, old Cold War foes, have engaged in tit-for-tat expulsions of diplomats.

The Trump administration expelled 15 Cuban diplomats in September 2017 after sharply drawing down U.S. embassy staff in Havana over a mysterious affliction that Washington said had affected American personnel there.

The Republican president has imposed new economic sanctions on Cuba and restricted travel to the island, steadily rolling back parts of the historic opening under his Democratic predecessor, Barack Obama.

Washington has made clear that a key objective of its pressure campaign is to force Cuba to abandon Maduro, something Havana has said it will never do. Trump, however, has stopped short of breaking off diplomatic relations with Cuba restored by Obama in 2015 after more than five decades of hostility.

(With input from Xinhua, Reuters)

(Cover: A view of the U.S. and Cuban flags prior to the signing of agreements between the Port of Cleveland and the Cuban Maritime authorities in Havana, Cuba, October 6, 2017. /Reuters Photo)