Paris Saint-Germain fell to a shock 2-0 loss to Reims at the Parc des Princes on Wednesday as headers from Hassane Kamara and Boulaye Dia gave the visitors a famous win.

The Ligue 1 champions, depleted by a spate of injuries, remain top of the table after seven games, but have already lost twice this season after defeat at Rennes last month.

It was PSG's first home loss in the league since a 2-0 reverse at the hands of Rennes in May 2018, ending an unbeaten run of 22 matches at the Parc.

PSG only lead second-placed Angers on goal difference, after Rachid Alioui's late double grabbed Stephane Moulin's side a 2-0 win at Toulouse.

"I'm disappointed with our performance. The first 10, maybe 15, minutes went well but then every minute that passed was worse and worse," said PSG coach Thomas Tuchel.

"We did not show what we are capable of doing — so defeat is deserved."

Neymar, who had scored late winners in each of his previous two Ligue 1 games, started alongside Eric Maxim Choupo-Moting and Pablo Sarabia up front, with Edinson Cavani, Kylian Mbappe and Mauro Icardi all still injured.

But the Brazilian, who failed to force through a return to Barcelona in the close-season, was a peripheral figure and was guilty of gifting Reims possession on numerous occasions.

Tuchel was also forced to play a makeshift midfield featuring full-back Juan Bernat, with Marco Verratti suspended.

The hosts made a slow start, despite Neymar going close with a free-kick, and fell behind just before the half-hour mark.

Reims, who also beat PSG 3-1 on the final day of last season, launched a rare attack and Hassane Kamara rose to powerfully head home Zimbabwean Marshall Munetsi's right-wing cross.

PSG's injury woes intensified further shortly before half-time as Choupo-Moting hobbled off to be replaced by Angel Di Maria, who had originally been rested and named as a substitute.

Reims came agonizingly close to doubling their advantage in first-half injury-time, as center-back Yunis Abdelhamid's header bounced narrowly passed the post.

PSG dominated possession for much of the second half without posing a serious threat, and Reims again came within centimeters of making it two as substitute Remi Oudin's low, left-footed effort struck the base of the post.

And Dia entered the fray before planting another fine header past the despairing dive of home goalkeeper Keylor Navas, sealing a deserved victory.