Liverpool surged 22 points clear at the top of the Premier League with a 4-0 win over Southampton, while Bruno Fernandes made his Manchester United debut in a goalless draw against Wolves on Saturday.

Mohamed Salah scored twice as the champions-elect equaled a Premier League record with a 20th straight home win at Anfield. Jordan Henderson doubled the European champions' lead with a smart finish on the hour mark.

Salah then produced two cool finishes in the final 20 minutes as Klopp's men took their tally of points to a remarkable 100 from the last possible 102.

Having completed his move from Sporting Lisbon on Thursday, in a deal worth an initial 61.2 million U.S. dollars, Fernandes went straight into the starting line-up at Old Trafford.

The 25-year-old midfielder delivered a composed display full of neat passing and took the role of chief creator. He kept Rui Patricio on his toes with a series of long-range drives, one of which the Wolves goalkeeper nearly spilled into his own net.

There was also a booking for Fernandes for pulling back Raul Jimenez in the second half of a tame clash that left sixth-placed United without a win in their last three league games.

Leicester and Chelsea consolidated their places in the top four in a 2-2 draw at the King Power Stadium.

Fourth-placed Chelsea sit five points clear of fifth-placed Sheffield United and six ahead of United and Wolves. Frank Lampard's men have won just four of their last 13 league games and needed two goals from center-back Antonio Rudiger just to claim a point.

Sheffield United are Chelsea's closest challengers as Chris Wilder's men earned a 1-0 win at Crystal Palace thanks to a calamitous own goal from Eagles goalkeeper Vicente Guaita.

Aston Villa's celebrations at reaching the League Cup final in midweek were short-lived as 10-man Bournemouth held on for a 2-1 win that lifted them up to 16th. Norwich are seven points adrift of safety at the bottom of the table after a 0-0 draw at Newcastle.

In Germany, Erling Braut Haaland insisted he needs to get fitter despite making it seven goals in three games for Borussia Dortmund with another double in Saturday's 5-0 Bundesliga thrashing of Union Berlin, while Bayern Munich usurped RB Leipzig at the top of the table.

The 19-year-old Haaland, who had netted five times in his first two appearances after signing from Salzburg, scored either side of half-time at Signal Iduna Park on his first Dortmund start.

Haaland's tally is the most by any Bundesliga player in their first three league matches.

Dortmund stay third in the table, three points behind leaders Bayern, who beat Mainz 3-1 to leave the top four clubs all within three points of each other.

Lewandowski netted his 22nd league goal of the season and Thomas Müller and Thiago Alcântara added two more to lift the defending champions to 42 points, one ahead of RB Leipzig who drew 2-2 at home to Borussia Mönchengladbach.

Fifth-placed Bayer Leverkusen lost ground as they went down 2-1 at Hoffenheim thanks to goals from striker Andrej Kramaric and Danish defender Robert Skov.

In Spain, Zinedine Zidane's double substitution at half-time transformed the Madrid derby on Saturday as Real Madrid edged past Atletico 1-0 to move six points clear at the top of La Liga.

Karim Benzema scored the winner at the Santiago Bernabeu after Zidane's decisive intervention turned a contest that Atletico had dominated into another comfortable Real Madrid victory.

Second-place Barcelona can cut the gap back to three points by beating Levante at home on Sunday but Atletico now trail the leaders by 13.

While Diego Simeone's side were strong in the first half, they were yet again blunt in front of goal and then failed to respond when their opponents found a different gear.

This is Atletico's fifth game without a win and on this form, they might begin to worry about missing out on Champions League qualification.

In France, Neymar helped Ligue 1 leaders Paris Saint-Germain to a 5-0 win over nine-man Montpellier.

Neymar, with his hair dyed pink, shook off an injury scare and raged with the match officials while Pablo Sarabia, Angel Di Maria, Kylian Mbappe and Layvin Kurzawa all scored along with a Daniel Congre own goal as PSG went 13 points clear of Marseille at the top of the table.

Neymar warmed up with a shirt bearing the name of Kobe Bryant and the number 24 of the basketball star who was killed in a helicopter crash last weekend.

While Neymar didn't score, having to settle just for one assist, he produced his usual tricks, provoked the opposition, and required lengthy treatment at the end of the first half after appearing to hurt his ribs as he grappled for the ball with Montpellier's Arnaud Souquet.

Unhappy with some of the treatment reserved for him, Neymar was booked for dissent in the first half and was then caught by television cameras angrily remonstrating in Portuguese with the fourth official in the tunnel at half-time.

Tuchel was also forced to answer questions about Mbappe's angry reaction to being taken off midway through the second half, as Edinson Cavani came on for a first appearance since a January move to Atletico Madrid fell through.

"It doesn't look good, but we are not the only club where players react like that," the coach said.

"This team shows how professional and focused they are every day, but this gives the impression it's not always like that and I'm sad because it's not necessary.

"I explained to him why he came off and that will be that. I always make decisions for sporting reasons. This is football, not tennis, and you have to respect everyone," he added.

Marseille go to Bordeaux on Sunday looking for a first win there in 43 years, while Rennes strengthened their grip on third by scoring twice in injury time to claim a 3-2 win over Nantes on Friday.

Elsewhere on Saturday, Monaco's problems continued as they had two men sent off in the first half and lost 3-1 at Nimes. They remain 13th. Victor Osimhen's late penalty gave Lille a 2-1 victory at Strasbourg to leave them fourth.