2020 has been a year filled with disruptions and uncertainties, and nothing is left untouched. The way we live, work, and think have all been changed. Facing the challenges of science has never been this important. CGTN organized this TV forum, “Science in an Uncertain World”, to discuss why science matters, how it works and what we should do. This forum is organized by CGTN Think Tank and the National Communication Center for Science and Technology, CAST.