Some U.S. health officials are conceding that monkeypox is probably not going away anytime soon. 

The disease's spread is slowing, but the virus is so widespread that elimination is unlikely, the U.S. Centers for Disease Control and Prevention (CDC) said. That conclusion was in a recent CDC report and echoed Friday by Marc Lipsitch, director of science in the agency's disease-forecasting center. 

Lipsitch hesitated to say monkeypox is permanently here to stay, but he said it stands to be a continuing threat for the next few years. 

"It's in many geographic locations within the country," as well as in other countries, said Lipsitch. "There's no clear path in our mind to complete elimination domestically."

The virus has mainly spread among gay and bisexual men, though health officials continue to stress that anyone can be infected. It's important that people at risk take steps to prevent spread and that vaccination efforts continue, Lipsitch said.

The CDC report contained some good news: The U.S. outbreak seems to have peaked in early August. The average number of daily cases being reported – fewer than 150 – is about a third of what it was reported in the middle of the summer, and officials expect the decline will continue for at least the next several weeks.

Lipsitch attributed the good news to increasing vaccinations, cautious behavior by people at risk and infection-derived immunity in the highest risk populations. 

Doctor Tom Inglesby, director of the Johns Hopkins Center for Health Security, agreed that it's unlikely that the spread of monkeypox will stop in the U.S. anytime soon, but he said it's still possible in the long term. 

If domestic transmission were stopped, infections may still continue if people catch the virus while traveling internationally, he said. But the declining cases make it seem like "we've turned a real corner." 

"The efforts underway are succeeding, and should be continued, if not intensified," he said. 

With case numbers going down, this is a good time for local health departments to take a new stab at doing intensive contact tracing to try to stop chains of transmission, he said. 

Monkeypox is endemic in parts of Africa, where people have been infected through bites from rodents or small animals, but it wasn't considered a disease that spreads easily among people until May when infections emerged in Europe and the U.S.

Though cases have been declining, the proportion of new cases that have information about recent sexual contact is also down, officials said. That's causing a growing blind spot about how the virus may be spreading, Lipsitch noted.