Four people were killed, 27 others wounded in clashes between Pakistani former Prime Minister Imran Khan's supporters and the country's police in Peshawar, local media Geo TV reported on Wednesday, citing a spokesperson from a local hospital.

Police have arrested 945 protesters in Pakistan's Punjab following the arrest of Imran Khan, a spokesperson for the police said on Wednesday.

According to police, 130 police officers were injured and 25 police vehicles and more than 14 government buildings were set on fire.

Khan was arrested on Tuesday by the National Accountability Bureau (NAB) under alleged charges of corruption and corrupt practices.

Shah Mahmood Qureshi, a senior vice president of Khan's Tehreek-e-Insaf party, appealed for peaceful demonstrations on Wednesday, urging followers not to destroy property.

"Don't damage public property; don't attack offices, as we are peace lovers," he said. Qureshi said the party is considering challenging Khan's arrest in the Supreme Court.

Khan's supporters clashed with police in many cities on Tuesday and stormed military buildings in Lahore and Rawalpindi, according to witnesses and videos shared by his party, which has called for a "shutdown" across the country.

Amid the violence, Pakistan's telecommunication authority on Tuesday blocked social media, including Twitter. The government also suspended internet service in the capital Islamabad and other cities. 

Pakistan's Information Minister Marriyum Aurangzeb told broadcaster Geo News on Wednesday that the protests were not a public response to Khan's arrest but a planned move by his party.

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(With input from agencies)