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A vial of the influenza vaccine is displayed at a pharmacy in San Francisco, California, January 22, 2018. /CFP
The United States has started a clinical trial of an experimental universal influenza vaccine developed by researchers at the U.S. National Institutes of Health (NIH), the agency said on Monday.
The trial has begun enrolling volunteers at Duke University in Durham, North Carolina. This Phase 1 trial will test the experimental vaccine, known as H1ssF-3928 mRNA-LNP, for safety and its ability to induce an immune response, according to the NIH.
The trial will enroll up to 50 healthy volunteers aged 18 through 49. Three groups of study participants, 10 participants each, will be vaccinated with 10, 25 and 50 micrograms of the experimental vaccine, respectively.
After evaluating the data to determine an optimum dosage, an additional 10 participants will be enrolled to receive the optimum dosage.
The study also will include a group of participants who will receive a current quadrivalent seasonal influenza vaccine. This will allow the researchers a point of direct comparison between the immunogenicity and safety of the candidate vaccine and available seasonal flu vaccines, according to the NIH.
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Disinformation report hotline: 010-85061466