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Copyright © 2024 CGTN. 京ICP备20000184号
Disinformation report hotline: 010-85061466
An illustration shows coronary angioplasty, a procedure used to widen blocked or narrowed coronary arteries (the main blood vessels supplying the heart). /CFP
Chinese scientists have identified a group of gene mutations that are correlated to an elevated risk of coronary heart disease (CHD).
Their findings have been published in the medical journal JAMA Cardiology.
The study, which was published online on January 10, stated that the elevated CHD risk attributed to those mutations was not negligible, promoting the early prediction of and personalized prevention and treatment of coronary heart disease.
A screenshot of the study published in the medical journal JAMA Cardiology.
In a cohort study of 6,181 Chinese individuals, the researchers from Fuwai Hospital under the Chinese Academy of Medical Sciences found that the clonal hematopoiesis of indeterminate potential (CHIP), the presence of a kind of stem cell caused by leukemia-causing mutations, was associated with a 42 percent increase in CHD risk in 1,100 CHIP carriers compared with those without CHIP.
The cohort study used data from three prospective cohorts in the project Prediction for Atherosclerotic Cardiovascular Disease Risk in China. Participants without cardiovascular disease or cancer at baseline were enrolled in 2001 and 2008 and had a median follow-up of 12.17 years extending into 2021.
(With input from Xinhua)