The United States depleted a substantial share of its advanced missile interceptors to defend Israel against Iranian attacks in the recent 12-day conflict. The operation consumed an estimated $800 million and strained global stockpiles, according to U.S. media reports.

The U.S. deployed an estimated 15–20 percent of its global stockpile of Terminal High-Altitude Area Defense (THAAD) missile interceptors during the conflict, where Israel and the U.S. struck Iranian nuclear facilities and Iran retaliated with missile attacks, Newsweek reported, citing the Bulgarian Military News and Military Watch Magazine outlets.

Amid concerns over dwindling supplies, the U.S. restocked interceptor missiles for the THAAD system it deployed in Israel in 2024, according to The Wall Street Journal.