A UPS cargo plane with three crew members onboard crashed during takeoff from Louisville Muhammad Ali International Airport on Tuesday. The flight was headed to Honolulu, Hawaii. Kentucky Governor Andy Beshear said at least 3 people were killed and 11 were injured in the crash. Plane carrying about 38,000 gallons of fuel ignited nearby buildings. Louisville is home to UPS Worldport, the company's largest global air cargo hub, handling hundreds of thousands of packages every hour.