International reactions to the US-Israeli strikes on Iran, now entering their fifth day, have included condemnations of the military action and widespread calls for de-escalation and peace.

Chinese Foreign Minister Wang Yi said Tuesday that China calls for an immediate cessation of military operations to prevent the conflict from further escalating and spiraling out of control. "The use of force cannot truly resolve the issue," Wang said. "Instead, it will create new problems and grave repercussions."

Oman's Foreign Minister Badr bin Hamad al-Busaidi said on Tuesday that off-ramps for de-escalation remain "available" and urged "an immediate ceasefire and a return to responsible regional diplomacy."

Oman had been mediating indirect talks between Iran and the United States before the US-Israeli strikes starting on Saturday.

Russian Foreign Minister Sergey Lavrov on Tuesday described US-Israeli strikes against Iran as an act of aggression and called for an immediate cessation of hostilities, warning that attacks on Iran could push not only Tehran but its neighbors to seek to acquire nuclear weapons. The widening conflict in the region raises the risk that nuclear proliferation issues could spin out of control, Lavrov said.

India on Tuesday renewed its call for dialogue and diplomacy, urging an early end to the ongoing conflict. In a statement, the Ministry of External Affairs reaffirmed that it has urged all sides to exercise restraint, avoid escalation and prioritize the safety of civilians.

The UAE Ministry of Foreign Affairs on Tuesday reiterated the country's call for de-escalation and dialogue to prevent further deterioration of the situation in the region.

The ministry also reaffirmed that it has not changed its defensive posture though having detected more than 1,000 Iranian attacks, a number exceeding the total number faced by all other targeted countries combined. It stated that it remains a non-party to the ongoing conflict.

Spanish Prime Minister Pedro Sanchez on Saturday condemned US-Israeli "unilateral military action" against Iran, calling it an "unjustified" and "dangerous military intervention" outside the bounds of international law.

In a firm break from US policy, the Sanchez government has also denied US permission to use Spanish bases or facilities for military operations against Iran, saying any such use must comply with international law.

While criticizing the initial strikes, Spain also condemned Iran's retaliatory attacks on Gulf countries.

Madrid called for Europe to adopt a stance of "balance and moderation," urging all parties to pursue de-escalation and a return to diplomatic negotiations.

In a social media post on Tuesday, Pakistani Defense Minister Khawaja Asif called Israel a driving force behind instability in the Muslim world and a "threat to humanity," warning that the war on Iran threatens Pakistan's security.

French President Emmanuel Macron said Tuesday that the military operations launched by the United States and Israel were conducted "outside international law" and could not be approved by France.

Canadian Prime Minister Mark Carney on Tuesday expressed regret over the failure of the international order in the Middle East, imploring all parties, including the US and Israel, to "respect the rules of international engagement."

"Canada calls for a rapid de-escalation of hostilities and is prepared to assist in achieving this goal," he told reporters in Sydney during his visit to Australia, according to a statement issued Tuesday.

Canada reaffirms that international law binds all belligerents, Carney said, noting that "resolution of this crisis requires commitment to a broader political solution" and diplomatic engagement "is essential to avoid a wider and deeper conflict."

(With input from Xinhua)