At least three people were killed in overnight drone attacks by Ukrainian forces on the cities of Khimki and Mytishchi in the Moscow region, regional governor Andrei Vorobyov said on Sunday.

Ukraine launched a major long-range drone attack targeting multiple regions inside Russia, including a massive oil refinery, after days of Russian missile and drone strikes on Ukraine.

"In Khimki, a woman was killed when a UAV (unmanned aerial vehicle) struck a private house. Another person remains trapped under the rubble. Two men died in the village of Pogorelki (in Mytishchi). There, drone debris hit a house under construction," the governor said on the social media platform Max.

On Saturday night, several construction workers were injured, and four residential buildings were damaged as a result of a drone attack on the Moscow Refinery.

Moscow Mayor Sergei Sobyanin said on Max that according to preliminary data, 12 people were wounded, adding that the plant's operations have not been disrupted.

He also said that over the past 24 hours, 120 Ukrainian drones had been shot down over Moscow by air defense forces.

Russia's defense ministry ​said 556 drones had been downed over ​the country, including the Moscow region, overnight and into ‌the morning.

(With input from agencies)