Cristiano Ronaldo has become the first player to score 400 goals in Europe's top five leagues as Juventus dropped points for the first time this season following a 1-1 Serie A draw with Genoa on Saturday.

The Portuguese striker's fifth league goal for Juve carried him to the milestone, adding to his 84 strikes for Manchester United in the Premier League and 311 for Real Madrid in La Liga.

Ronaldo is now 10 goals ahead of Lionel Messi's tally of 390 goals scored in Europe's main leagues. The Argentine was on target for Barcelona in their 4-2 La Liga win against Sevilla.

Ronaldo put Juventus ahead in the 18th minute during a dominant first half, but sloppy defending from the hosts allowed Daniel Bessa to draw Genoa level after the break and end Juve's 10-match winning streak in all competitions.

Juventus coach Massimiliano Allegri blamed his players for being sidetracked by their Champions League trip to Manchester United on Tuesday.

“We went from being frenetic to falling asleep and vice-versa. We should have had our mind on the job," Allegri went on to say, "I think it'll be a good lesson for us, as this is a wake-up call, so everyone can remember that nothing is to be taken for granted. Every match has to be won on the pitch in 90 minutes. Nothing is guaranteed or won before we've stepped on to the pitch."

Earlier, Roma were beaten 2-0 by SPAL courtesy of an Andrea Petagna penalty and a Kevin Bonifazi header either side of the break. The result leaves the capital club in sixth place before Sunday's games, 11 points adrift of Serie A leaders Juventus.

Meanwhile, Napoli closed the gap on Juventus to four points with a 3-0 win at Udinese on Saturday.